PTP company indigenizes MTT

0 Mar 09 2021 In بین‌المللی

Zharf Andishan Fnavar Zist Baspar whch one of the affiliated companies in Pardis Technology Park has indigenized MTT metrial.

MTT is used to determine the toxicity of different cells in biological and cellular laboratories.

MTT, which used to be an important substance, was always imported to medical, hospital, university and research centers, but it has now been completely indigenized.

Thiazolyl Blue Tetrazolium Blue (MTT) may be used in measurement of cell proliferation. MTT produces a yellowish solution that is converted to dark blue, water-insoluble MTT formazan by mitochondrial dehydrogenases of living cells.

he blue crystals are solubilized with acidified isopropanol and the intensity is measured colorimetrically at 570 nm. MTT has been used as a histochemical/cytochemical reagent and for the detection of NAD.

ADP-linked enzyme systems in tissue cannot be detected with MTT, due to binding of the cation by the cyanide trap used. MTT is rapidly reduced to the formazan, which chelates with nickel, copper, and cobalt; the cobalt chelate has been used in oxidative systems.

This product, which competes with the American samples in terms of quality, is sold at a very reasonable price and lower than the foreign product (25-30% less).

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